GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs568617 | 1 | rs694994 | chr11:65653309 | SNX32 | chr11:65601410-65621170:+ | 0.63 | 5.51 | 9.72E-7 | Crohn's disease |
| UVM | cis | rs2071518 | 1 | rs6983056 | chr8:120446127 | NOV | chr8:120428552-120436678:+ | 0.63 | 5.13 | 3.9E-6 | Blood pressure |
| UVM | cis | rs2071518 | 1 | rs6983393 | chr8:120446349 | NOV | chr8:120428552-120436678:+ | 0.63 | 5.13 | 3.9E-6 | Blood pressure |
| UVM | cis | rs2071518 | 1 | rs6990760 | chr8:120444628 | NOV | chr8:120428552-120436678:+ | 0.62 | 5.12 | 3.98E-6 | Blood pressure |
| UVM | cis | rs2071518 | 1 | rs6993389 | chr8:120457102 | NOV | chr8:120428552-120436678:+ | 0.6 | 4.99 | 6.33E-6 | Blood pressure |
| UVM | cis | rs2071518 | 1 | rs6997943 | chr8:120463608 | NOV | chr8:120428552-120436678:+ | -0.6 | -4.7 | 1.79E-5 | Blood pressure |
| UVM | cis | rs7017914 | 1 | rs7007450 | chr8:71640269 | XKR9 | chr8:71581600-71648176:+ | 0.87 | 8.96 | 2.49E-12 | Bone mineral density |
| UVM | cis | rs2071518 | 1 | rs7014927 | chr8:120431049 | NOV | chr8:120428552-120436678:+ | 0.6 | 4.95 | 7.51E-6 | Blood pressure |
| UVM | cis | rs2071518 | 1 | rs7015188 | chr8:120454085 | NOV | chr8:120428552-120436678:+ | -0.6 | -4.94 | 7.63E-6 | Blood pressure |
| UVM | cis | rs2071518 | 1 | rs7016011 | chr8:120454474 | NOV | chr8:120428552-120436678:+ | 0.6 | 4.99 | 6.33E-6 | Blood pressure |
| UVM | cis | rs7017914 | 1 | rs7017914 | chr8:71591203 | XKR9 | chr8:71581600-71648176:+ | 0.88 | 9.19 | 1.07E-12 | Bone mineral density |
| UVM | cis | rs703842 | 1 | rs703842 | chr12:58162739 | TSFM | chr12:58176536-58191367:+ | 0.57 | 5.04 | 5.32E-6 | Multiple sclerosis |
| UVM | cis | rs11190604 | 1 | rs7070776 | chr10:102264672 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs7071271 | chr10:102264824 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs7072216 | 1 | rs7072216 | chr10:100156853 | PYROXD2 | chr10:100143323-100174978:- | 0.79 | 6.18 | 8.28E-8 | Metabolite levels |